Publications2

(17) Newby GA†, Kayatekin C†. "Microbial specialization by prions." Prion. 2018 Jun 20. Invited Extra Views. Link to paper. †Co-corresponding author

(16) Kayatekin C†, Amasino A, Gaglia G, Flannick J, Bonner JM, Fanning S, Narayan P, Barrasa MI,Pincus D, Landgraf D, Nelson J, Hesse WR, Costanzo M, T2D-GENES Consortium, Myers CL, Boone C, Florez JC, Lindquist S. 2018 “Translocon declogger Ste24 protects against IAPP oligomer-induced proteotoxicity.” Cell. 2018 Mar 22;173(1):62-73.e9. doi: 10.1016/j.cell.2018.02.026. Link to paper. †corresponding author

(15) Newby GA*, Kiriakov S*, Hallacli E*, Kayatekin C, Tsvetkov P, Mancuso CP, Bonner JM, Hesse WR, Chakrabortee S, Manogaran AL, Liebman SW, Lindquist S, Khalil AS. 2017 “A genetic tool to track protein aggregates and control prion inheritance.” Cell. 171(4):966-979. doi: 10.1016/j.cell.2017.09.041. Link to paper.

(14) Chakrabortee S, Kayatekin C, Newby GA, Mendillo ML, Lancaster A, Lindquist S. 2016. “Luminidependens (LD) is an Arabidopsis protein with prion behavior.” Proc Natl Acad Sci U S A. May 24;113(21):6065-70. Link to paper.

(13) Kayatekin C*, Matlack KE*, Hesse WR, Guan Y, Chakrabortee S, Russ J, Wanker EE, Shah JV, Lindquist S. 2014 “Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1” Proc Natl Acad Sci U S A. 111(33):12085-90. Link to paper.

(12) Kathuria SV, Kayatekin C, Barrea R, Kondrashkina E, Graceffa R, Guo L, Nobrega RP, Chakravarthy S, Matthews CR, Irving TC, Bilsel O. 2014 “Microsecond barrier-limited chain collapse observed by time-resolved FRET and SAXS. J Mol Biol. 426(9):1980-94. Link to paper.

(11) Frederick KK, Debelouchina GT, Kayatekin C, Dorminy T, Jacavone AC, Griffin RG, Lindquist S. 2014 “Distinct prion strains are defined by amyloid core structure and chaperone binding site dynamics.” Chem Biol. 21(2):295-305. Link to paper.

(10) Chai L, Romero D, Kayatekin C, Akabayov B, Vlamakis H, Losick R, Kolter R. 2013 “Isolation, characterization, and aggregation of a structured bacterial matrix precursor.” J. Biol. Chem.288(24):17559-68. Link to paper.

(9) Broering TJ, Wang H, Boatright NK, Wang Y, Baptista K, Shayan G, Garrity KA, Kayatekin C, Bosco DA, Matthews CR, Ambrosino DM, Xu Z, Babcock GJ. 2013. “Identification of human monoclonal antibodies specific for human SOD1 recognizing distinct epitopes and forms of SOD1.” PLoS One 8(4):e61210. Link to paper.

(8) Kayatekin C, Cohen NR, Matthews CR. 2012. ”Enthalpic Barriers Dominate the Folding and Unfolding of the Human Cu, Zn Superoxide Dismutase Monomer.” J. Mol. Biol. 424(3-4):192-202. Link to paper.

(7) Taipale M, Krykbaeva I, Koeva M, Kayatekin C, Westover KD, Karras GI, Lindquist S. 2012. “Quantitative analysis of Hsp90::client interactions reveals principles of substrate recognition.” Cell150(5):987-1001. Link to paper.

(6) Kayatekin C, Zitzewitz JA, Matthews CR. 2010. “Disulfide-reduced ALS variants of Cu, Zn superoxide dismutase exhibit Increased populations of unfolded species” J. Mol. Biol. 398:320-31. Link to paper.

(5) Svensson A-KE, Bilsel O, Kayatekin C, Adefusika JA, Zitzewitz JA & Matthews CR. 2010. ”Metal-free familial amyotrophic lateral sclerosis variants of human Cu, Zn-superoxide dismutase have enhanced populations of monomeric species.” PLoS One 5(4): e10064. Link to paper.

(4) Kayatekin C, Zitzewitz JA, Matthews CR. 2008. “Zinc binding modulates the entire folding free energy surface of human Cu,Zn superoxide dismutase.” J. Mol. Biol. 384(2):540-55. Link to paper.

(3) Wu Y, Kondrashkina E, Kayatekin C, Matthews CR, Bilsel O. 2008. “Microsecond acquisition of heterogeneous structure in the folding of a TIM barrel protein.” PNAS 105(36):13367-72. Link to paper.

(2) Arai M, Kondrashkina E, Kayatekin C, Matthews CR, Iwakura M, Bilsel O. 2007. “Microsecond hydrophobic collapse in the folding of Escherichia coli dihydrofolate reductase, an alpha/beta-type protein.” J. Mol. Biol. 368(1):219-29. Link to paper.

(1) Bilsel O, Kayatekin C, Wallace LA, Matthews CR. 2005. “A microchannel solution mixer for studying microsecond protein folding reactions.” Rev. Sci. Instrum. 76.

*Equally contributing authors